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KMID : 0882420050690060706
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Korean Journal of Medicine
2005 Volume.69 No. 6 p.706 ~ p.710
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Two different cases of episodic angioedema with eosinophilia
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박찬선/Park CS
이성숙/임정우/안정민/이태훈/조유숙/문희범/Lee SS/Lim JW/An JM/Lee TH/Cho YS/Moon HB
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Abstract
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Episodic angioedema with eosinophilia (Gleich’s syndrome) is characterized by recurrent angioedema, fever, weight gain and peripneral eosinophilia. The symptoms and clinical course differ markedly from the idiopathic hypereosinophilic syndrome, including an absence of end organ involvement and a better prognosis. A transient variant, mainly reported in Japan, which is limited to a single attack, is usually less severe than the episodic type. Here we describe two young patients, one of those is the episodic type and the other is the transient type. We suggest that episodic angioedema with eosinophilia is not rare, and should be widely recognized as a new clinical entity for accurate and prompt diagnosis. Awareness and distinction from the hypereosinophilic syndrome is important because of the favorable prognosis and rapid response to corticosteroid therapy.
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KEYWORD
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